Читать книгу Snyder and Champness Molecular Genetics of Bacteria - Tina M. Henkin - Страница 42

Also in 1961, Francis Crick and his collaborators used phages and bacteria to show that the genetic code is unpunctuated, three lettered, and redundant. These researchers also showed that not all possible codons designate an amino acid and that some are “nonsense.” These experiments laid the groundwork for Marshall Nirenberg and his collaborators to decipher the genetic code, in which a specific three-nucleotide set encodes one of 20 amino acids. The code was later verified by the examination of specific amino acid changes due to mutations in the lysozyme gene of phage T4.