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Adoption studies

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Complete adoption studies are useful in separating the common environmental effects since adoptive parents and their adoptive offspring share only environmental sources of variance, whilst the adoptees and their biologic parents share only genetic sources of variance. One of the largest series, based on over 5000 subjects from the Danish adoption register, which contains complete and detailed information on the biologic parents, showed a strong relationship between the BMI of adoptees and biologic parents across the whole range of body fatness but none when compared with the adoptive parents [1]. The Danish group has also shown a close correlation between BMI of adoptees and their biologic full siblings who were reared separately by the biologic parents of the adoptees, and a similar but weaker relationship with half‐siblings [4].

Clinical Obesity in Adults and Children

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