Читать книгу Clinical Obesity in Adults and Children - Группа авторов - Страница 73

The assessment of children with severe obesity and indeed adults should be directed at screening for potentially treatable endocrine and neurological conditions and identifying genetic conditions so that appropriate genetic counseling and, in some cases, treatment can be started. Clinically, it remains useful to categorize the genetic obesity syndromes as those with dysmorphism and/or developmental delay and those without these features (Tables 4.1 and 4.2). There are more than 30 Mendelian disorders with obesity as a clinical feature but often associated with learning difficulties, dysmorphic features, and organ‐specific developmental abnormalities (i.e. pleiotropic syndromes). For a comprehensive list of syndromes in which obesity is a recognized part of the phenotype, see Online Mendelian Inheritance in Man (OMIM), www.ncbi.nlm.nih.gov/omim.