Читать книгу Secondary Metabolites of Medicinal Plants - Bharat Singh - Страница 9

Abutilon indicum L. (Fam. – Malvaceae) aerial parts and roots have been used for treating inflammations, ulcer, diarrhea, pains, stomach ailments, diabetes, and wounds (Jayaweera 2006; Khare 2010; Ushakumari et al. 2012). Traditional practitioners used the plant to treat diseases like gout, tuberculosis, ulcer, jaundice, leprosy, gonorrhea, bronchitis, lumbago malarial fever, piles, dental problems, and other bleeding disorders (Algesaboopathi 1994; Yoganarsimha 2000; Muthu et al. 2006; Nisha and Rajeshkumar 2010). The grounded leaves of this plant species mixed with wheat flour are used for treating uterus in Indian system of medicine (Mohapatra and Sahoo 2008). There are reports of topical application of leaf paste on the spot of scorpion bite to relieve pain (Dinesh et al. 2013). Flowers of this plant are used by tribal population in Southern India to increase the concentration of semen in men (Ramachandran 2008). Abutilon indicum is found in tropical and subtropical regions of India–China and has therapeutic uses as febrifuge, anthelmintic, antiemetic, and anti-inflammatory and in urinary and uterine discharges, piles, and lumbago (Nadkarni 1954; Chopra et al. 1958; Subramanian and Nair 1972; Badami, et al. 1975; Gaind and Chopra 1976). Seeds are used in a decoction to treat cough (Yasmin et al. 2008). Ethyl acetate fraction of Abutilon grandiflorum showed antimalarial activity (Beha et al. 2004). A. indicum demonstrated hypoglycemic (Seetharam et al. 2002), anxiolytic (Tirumalasetty et al. 2011), antiulcer (Malgi et al. 2009), hepatoprotective (Porchezhian and Ansari 2005), antimicrobial (Poonkothai 2006; Edupuganti et al. 2015), anticonvulsant (Golwala et al. 2010), antidiarrheal (Chandrashekhar et al. 2004), antioxidant (Yasmin et al. 2010), antimicrobial, and anti-inflammatory (Tripathi et al. 2012; Kaladhar et al. 2014) activities (Abat et al. 2017).

Gossyptin-7-glucoside, cyanidin-3-rutinoside, alantolactone and isoalantolactone, gossypetin-8-glucoside (Subramanian and Nair 1972; Sharma and Ahmad 1989), β-sitosterol, fatty acid esters of stearic and palmitic acid and flavonoids (Yasmin et al. 2008), β-amyrin 3-palmitate, squalene, β-sitosterol and stigmasterol (Macabeo and Lee 2014), fumaric acid, caryophyllene, caryophyllene oxide, geraniol, elemene, methyl indole-3-carboxylate, hinesol, cubenol, phytol, γ-sitosterol, lupeol, palmitic acid, 1-lycoperodine, 1-methoxycarbonyl-β-carboline, tetracontane, n-tetracosane, 3-hydroxy-β-damascone, 3-hydroxy-β-ionol, scopoletin, scoparone, methyl coumarate, trans-p-coumaric acid, abutilon A, quercetin, eugenol (4-allyl-2-methoxyphenol), syringic acid, benzoic acid, vanillic acid, gallic acid, N-feruloyl tyrosine, caffeic acid, p-β-D-glucosyloxybenzoic acid, 4-hydroxy-3-methoxy-trans-cinnamic acid methyl ester, methyl caffeate, p-hydroxybenzaldehyde, vanillin, syringaldehyde, 4-hydroxyacetophenone, methylparaben, β-sitosterol, stigmasterol, (R)-N-(10-methoxycarbonyl-20-phenylethyl)-4-hydroxybenzamide, p-β-D-glucosyloxybenzoic acid, p-hydroxybenzoic acid, and caffeic acid were identified from A. indicum (Gaind and Chopra 1976; Kuo et al. 2008; Pandey et al. 2011; Shanthi et al. 2011; Hussain et al. 2012; Khan et al. 2015). Similarly, pakistamide C has been isolated from the ethyl acetate-soluble fraction of the methanolic extract of Abutilon pakistanicum (Ali et al. 2014).