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1.2.1.2 Mesoporous Silica Nanoparticles
ОглавлениеMesoporous silica nanoparticles (MSNPs) are another important group of inorganic nanomaterials (Figure 1.1b). These nanoparticles are also considered ideal candidates for biomedical applications due to their controllable morphologies, mesostructures with biocompatibility, and easy functionalization ability (Dykman and Khlebtsov 2012; Liu and Xu 2019). The presence of numerous silanol groups on the surface of MSNPs make them hydrophilic; moreover, their functionalization using a variety of groups helps to achieve controlled holding/release of cargo molecules. In addition, the large internal surface area and pore capacity of mesoporous materials allow a high loading of cargo molecules and also prevent them from escaping into water easily by dissolving in an aqueous environment (Jafari et al. 2019). These advantages enhance the effectiveness of the MSNP‐based delivery system and allow a specific amount of drugs to reach their therapeutic target (Li et al. 2012).