Читать книгу Nanobiotechnology in Diagnosis, Drug Delivery and Treatment - Группа авторов - Страница 54

Selenium nanocomposites are promising compounds with great potential for medicinal use. Nowadays, the main spectrum of beneficial use of these nanocomposites is associated with their use for the diagnosis and treatment of various diseases. In addition, these compounds can act as multifunctional platforms for targeted drug delivery and simultaneous detection of SeNPs in tissues due to their fluorescent ability. Prospects for the use of SeNPs are associated with the synergism of their antitumor activity and ability for target delivery of antitumor agents. Alzheimer's disease and diabetes are two quite common severe diseases in which the use of selenium nanoparticles may be promising.

The antibacterial activity of SeNPs is of particular interest. This area is particularly relevant because of the increase in the amount of antibacterial resistance in pathogens against main antibacterial drugs. At the same time, the reaction of damaged tissues to the introduction of selenium nanocomposites is ambiguous, and additional studies are needed to determine the effects of inflammation and wound healing. Rational design of multifunctional nano platforms with drugs is a promising strategy for simultaneous diagnosis, real‐time monitoring, and treatment.