Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 136

Adult stem cells are partially committed to lineage, unlike embryonic stem cells, so they have the capacity to give rise to a particular germ layer. For example, post-transplant adult hematopoietic stem cells in the leukemia patient can repopulate the bone marrow for generating all blood cell lineages. The multipotent adult stem cell however cannot produce ectodermal or endodermal cell lineages. Unipotent stem cells have increased capacity of replication but they can only differentiate into a specific cell lineage. Adult stem cells have greater proliferation capacity and ability to repair or repopulate tissue in comparison to adult differentiated cells, although adult differentiated cells only give rise to cells of identical lineage.