Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 152

One of the basic functions of hematopoietic stem cells is self-renewal, the reason for the multiple applications in the treatment of diseases. Over the course of years, scientists have endeavored to culture human hematopoietic stem cells but it has proven difficult as cultured HSCs rush to differentiate, although many studies have been conducted on animal cells. Telomerase is an enzyme that expands the regions of DNA called telomeres (present at the ends of the chromosomes), and long-term stem cells have been linked to increased telomerase activity and thus the properties of self-renewal.

Figure 1 Haematopoietic stem cell differentiation