Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 151

There are two types of hematopoietic stem cells (HSCs): long term and short term. As the names suggest, long-term HSCs proliferate for a lifetime while short-term HSCs only last for a period of up to four months and are usually committed progenitors. It is difficult to differentiate between these two types because no set markers have been identified for them; however, Irving Weissman did propose a set of markers in humans, which were similar to those found in mice HSCs.

Glycoproteins CD34+ and CD133+ identify human hematopoietic progenitor cells. Most human marrow or blood CD34+ or CD133+ cells are committed progenitors, and only a small minority are long-term stem cells.