Читать книгу The Peripheral T-Cell Lymphomas - Группа авторов - Страница 53

ALCL is characterized by sheets of CD30 positive anaplastic large cells. Systemic ALK‐negative ALCL nodal lymphomas have all the other morphological and phenotypical features of a CD30 positive cytotoxic ALCL except ALK expression [73]. DNMT3 and TET2 mutations have been identified in some cases, albeit comparatively few compared with AITL and PTCL‐Tfh [74].