Читать книгу Biological Mechanisms of Tooth Movement - Группа авторов - Страница 50

Orthodontic movement of teeth to a new position in the dental arch is the result of a highly complex biological process in response to the applied force. The PDL and the alveolar bone with their different cell types and ECM play a dominant role in activating the tissue response to enable movement. Many molecules have been implicated in this response, but a well‐integrated model representing a unified scheme is still incomplete.

The most recent model is given in the systematic review by Vansant et al. (2018) on the expression of biological mediators during OTM which is based on the model by Henneman et al. (2008) (Figure 3.16). Future research will fill in the gaps of knowledge that still exist. Every patient differs biologically and with increasing knowledge of the biological processes involved in OTM we may be able to design a personalized approach for each individual patient based on his or her biological profile. This will hopefully make the process of OTM more efficient than the standard approach we offer our patients today.

Figure 3.16 Theoretical model of orthodontic tooth movement (OTM) based on the model by Henneman et al. (2008).

(Source: Vansant et al., 2018. Reproduced with permission of Elsevier.)