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The team decided that the database must adhere to the following guidelines:

1. The registry should be Health Insurance Portability and Accountability Act (HIPAA) compliant. Although the registry would initially be for use internally, it should be migratable to other sites in the future.

2. This system should be able to retrieve demographic data from the current hospital electronic medical records (EPIC, CERNER, and Leksell GammaPlan^®, etc.). The system should pull information from different sources and bring them together in a single registry.

3. It should have tools designed to capture more complex outcome variables.

4. The system should be accessible using any PC within the UPMC health care computer network. Ease of access was felt to be critical for timely and reliable data entry.

5. The registry will be used primarily for use internally but should have the capability to send data to other sites in the future.

6. It should be able to link to future QA clinical registries under development by both corporate and professional societies. The new registry should be able to successfully migrate all existing data collected since 1987.