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Differential Diagnosis

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The embryonal subtype should be differentiated from small cell tumours, olfactory neuroblastoma, small cell neuroendocrine carcinoma, and sinonasal melanoma. As aberrant keratin and neuroendocrine markers (synaptophysin/chromogranin) may occur in the alveolar subtype, immunohistochemical assessment for muscle markers (desmin/myogenin) is critical to this diagnosis.

Anterior Skull Base Tumors

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