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Differential Diagnosis

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Tumours to be differentiated from olfactory neuroblastoma include lymphoma, melanoma, small round cell (Ewing’s sarcoma/PNET) tumour, rhabdomyosarcoma, and adenoid cystic carcinoma (solid form). Immunohistochemical profiles including a spectrum of different cell lineages are crucial for diagnosis. The comparative characteristics of these tumours with other primitive sinonasal tumours are presented in Table 5.

Anterior Skull Base Tumors

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