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Using cosmeceutical ingredients like vitamin C to improve procedural outcomes and boost radiance following an HA/combination peel, or using vitamin K to reduce the chances of ecchymoses have proven themselves successful in the medical field [11]. It is always crucial to identify the recommended amount of time to resume using specific cosmeceuticals, i.e., vitamin A, vitamin C, vitamin E, niacinamide, growth factor serums, and peptides, among others [19].

When combining HAs with topical prescriptions, the results can be marvelous under the direction and care of a trained physician. For instance, salicylic acid is very commonly utilized in conjunction with topical prescriptions [20] like benzoyl peroxide (BP). When looking at data from using BP alone, BP with topical antibiotics, or topical antibiotics on their own, the results are far inferior when compared to BP with salicylic acid [20]. The superficial peel healing time may be accelerated by a topical prescription of desonide cream [21], which is a mild corticosteroid used for pruritis, erythema, and/or inflammation. On the contrary, the results throughout the recovery period from a superficial peel may be enhanced by pretreating the skin with a topical prescription of tretinoin 0.025–0.1%, or an AHA of 8–10% which should be applied at night for 2–4 weeks prior to the procedure and discontinued 3–5 days before the procedure [22].