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Amniotic fluid cell culture

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Amniotic fluid cell (AFC) culture is a routine procedure in cytogenetics laboratories that has evolved considerably since its first application in the 1970s. What has changed over the years are improved speed to the final report, success rate of cell culture, and quality of the chromosome banding. Due to optimized cell culture media, the use of growth factor supplements, high‐quality plastic ware, sophisticated incubators, and robotic cell harvest equipment, culture failures occur in less than 0.2 percent of all specimens processed by experienced laboratories.

Genetic Disorders and the Fetus

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