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Syringe toxicity and delayed transportation

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One serious hazard is transmittal of AF in toxic syringes or tubes.666, 667 AF samples should not be transported in syringes; rather, the fluid should always be promptly transferred and transported in conical centrifuge tubes with plastic caps, spinal tap tubes or similar specimen transport containers. Rubber‐capped tubes and stoppered syringes should not be used as storage or transport containers for AF. Problems reported in the United States prompted one manufacturer to recommend minimizing both the time of AF in the syringe and contact with the stopper attached to the plunger rod.

Although it is advisable to deliver AF samples to the laboratory without delay, in our experience with AF specimens transported by courier and various delivery services, cell viability is maintained for at least 5 days, assuming the sample is not exposed to extreme temperatures. There is one report of successful cell cultures after unfortunate delays of more than 2 weeks.668

Genetic Disorders and the Fetus

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