Читать книгу Manual of Equine Anesthesia and Analgesia - Группа авторов - Страница 336

 In humans, normal O2 consumption is 3–5 ml/100 g/minute, similar to that of working skeletal muscle.

 When the level of consciousness is depressed, the cerebral metabolic rate is decreased.

 Oxygen consumption decreases by approximately 20% during hypoglycemia, 40% during general anesthesia, 3% during sleep, and 15–20% during hypothermia.

 Drugs such as α2 adrenergic agonists and a propofol infusion decrease cerebral metabolic oxygen demand and provide some brain protection.

 Isoflurane decreases cerebral metabolic oxygen demand, but causes vasodilation.