Читать книгу Manual of Equine Anesthesia and Analgesia - Группа авторов - Страница 352

 May be achieved through use of:Mannitol (0.15–2.5 g/kg, IV over 20 minutes).Loop diuretics (e.g. furosemide 0.75–1.0 mg/kg, IV).Hypertonic saline (2–4 ml/kg 7.2%, IV over 10–15 minutes).Dimethylsulphoxide (DMSO) (1.0–2.0 g/kg as a 10% or 20% solution).Dexamethasone (0.3–0.6 mg/kg, IV) to reduce ICP is controversial and steroid use for treatment of traumatic brain injury is not recommended in people.Steroids stabilize blood–brain barrier permeability, but the gluconeogenic effects may worsen brain injury.

 Further decreases in ICP may be necessary through use of heavy sedation/anesthesia, tracheal intubation and mechanical ventilation with a specialized ventilator. This labor‐intensive procedure might not be possible, and is only feasible for foals.

 Glycemic control. Hyperglycemia is associated with increased mortality with head trauma. There is debate whether insulin should be used to control hyperglycemia, but glucose‐containing fluids and gluconeogenic drugs should be avoided.