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C Effect of EPI release from adrenals

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 EPI, because it has greater affinity for β receptors, has a more profound effect on cardiac stimulation than does NE. However, NE is a more potent vasoconstrictor.

 NE and EPI increase systemic vascular resistance, mean arterial pressure and cardiac output through their α‐ and β‐receptor activity. Heart rate is more likely to increase with EPI due to a stronger chronotropic effect, whereas it decreases with NE, as a result of a baroreflex in response to the increase in systemic vascular resistance.

Manual of Equine Anesthesia and Analgesia

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