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Diagnostic criteria

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The National Comprehensive Cancer Network recommended the following diagnostic criteria proposed by the International Working Group (IWG).55 Minimal diagnostic criteria for this disease include two prerequisites:

1 Stable cytopenia (for ≥6 months or ≥2 months if accompanied by a specific karyotype or bilineage dysplasia)

2 The exclusion of other potential disorders as a primary reason for dysplasia or cytopenia

In addition, the diagnosis of MDS requires ≥1 of three MDS‐related criteria:

1 Dysplasia (≥10% in ≥1 of the 3 major bone marrow lineages)

2 A blast cell count of 5% to 19%

3 A specific MDS‐associated karyotype (e.g. del(5q), del(20q), +8, or ‐7/del(7q))

Pathy's Principles and Practice of Geriatric Medicine

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