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A thorough history of the clinical course of the skin tumor is essential. Pertinent information gathered should include duration of presence of the mass and the rate of growth, as well as any change in growth rate. Knowledge of any previous aspiration cytology, biopsy, or histology results of the current or other tumors is important and may affect prognosis and treatment decisions. Details of any concurrent diseases are equally important, as they could include signs of paraneoplastic syndromes associated with the skin mass (e.g. gastrointestinal ulceration associated with mast cell tumors). A thorough physical examination is part of a routine clinical examination. A complete blood count, serum biochemistry, and urinalysis are part of a minimum database for many patients with cutaneous masses, who are often middle aged to older, to assess for concurrent pathologies before administration of general anesthesia and surgical intervention.