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This section covers CRISPR outsourcing solutions, but the same principles apply to other forms of gene editing technologies like TALENs and ZFNs. Although the tools and methods for application of genome editing technologies are becoming more accessible, some labs may choose to outsource partial or entire experiments on a fee‐for‐service basis. Genome editing CROs have invested considerable efforts on internal development and have amassed great knowledge on how the technology works, which translates to a high competence to design genome editing projects and troubleshoot problems. In addition, CROs enable researchers to conduct research without the need to purchase and maintain expensive equipment (e.g. flow sorter, or next‐generation sequencing instruments). CROs are also used when there is time pressure to deliver while internal resource is in short supply, or in cases where there is limited or no internal expertise. Such a business model has several advantages and disadvantages which need to be considered before proceeding with this option (Pichler and Turner 2007).