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Combinations of clinical signs

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There are some combinations/patterns of clinical signs that make the diagnostic options very limited, and it is entirely appropriate to consider them together; for example, the patient with PU/PD who is also polyphagic. If the PU/PD and polyphagia have been present for the same length of time, then they are almost certainly due to the same disorder, and it is quite appropriate to assess them together. There are very few conditions that will cause this pattern of clinical signs (e.g. diabetes mellitus, hyperthyroidism and hyperadrenocorticism), so it is quite appropriate to concentrate on these first.

Clinical Reasoning in Veterinary Practice

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