Читать книгу Catalytic Asymmetric Synthesis - Группа авторов - Страница 68

The merger of chiral Brønsted acid and photoredox catalyst was first reported by Knowles in 2013. The reductive coupling of ketones and hydrazones proceeded in a highly enantioselective manner to furnish syn‐1,2‐amino alcohols with excellent levels of diastereo‐ and enantioselectivities. The reaction was proposed to proceed via N‐centered radicals formed by the proton‐coupled electron transfer (PCET) activation of sulfonamide N‐H bonds [185]. A range of enantioselective reactions taking advantage of the combination of photoredox catalysis and chiral Brønsted acid catalysis has been reported [186]. For details, please see Chapter 8 [187].