Читать книгу Catalytic Asymmetric Synthesis - Группа авторов - Страница 69

In summary, development of chiral Brønsted acid catalysis up to 2020 has been discussed in this chapter. Significant advances in this area have emerged in the past decade, and numerous numbers of papers were published. Transformation mediated by chiral Brønsted acid started from the reaction with imines because of the basic nature of imine nitrogen. Functional groups activated by chiral Brønsted acids have been expanded to carbonyl, alkyne, alkene, alcohol, and others. A wide range of asymmetric reactions was catalyzed by the chiral Brønsted acid with high to excellent enantioselectivities. Furthermore, combination with other catalysts such as metal‐based catalysts and photoredox catalysts was successfully achieved. Relay catalysis and cooperative catalysis led to formation of complex molecules with high to excellent optical purity in simple operations. Its application to industrial process will be also expected. I hope this chapter will be useful to synthetic organic chemists who are interested in this active area, and will contribute to further advances.