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Vasovagal reactions are similar to those associated with whole blood donation, but may be reduced depending on the amount of volume replacement with the method. The symptoms include weakness, pallor, diaphoresis, bradycardia, cold clammy skin, lightheadedness or fainting, and, if severe, convulsions. The treatment is as described for whole blood donors. Because the donors are usually experienced whole blood donors, they rarely experience vasovagal reactions.

Table 4.5 Potential complications and adverse reactions to cytapheresis donation.