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Cover: The protein-DNA complex on the front cover is an image of bacteriophage T7 DNA polymerase (red) complexed with a DNA primer-template (gold), as resolved by a combination of X-ray crystallography and cryo-electron microscopy by Gao et al. (2019) (see Further Reading in Chapter 2 for complete citation; PDB ID 6N7W). The protein-DNA complex on the back cover and spine is an image of the human uracil-DNA glycosylase (red) complexed with a short duplex DNA (gold) with a uracil-like residue, as resolved by X-ray crystallography by Parikh et al. (1998) (see Further Reading in Chapter 10 for complete citation; PDB ID 1SSP). Both images were prepared using the web-based visualization system iCn3D (Wang et al., 2019; full citation and web site address on page viii) with coordinates from the Protein Data Bank (www.rcsb.org; Berman et al., 2000; full citation on page viii).

REPLICATING AND REPAIRING THE GENOME

From Basic Mechanisms to Modern Genetic Technologies

Copyright © 2020 by World Scientific Publishing Co. Pte. Ltd.

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ISBN 978-981-121-569-8 (hardcover)

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