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About the Author

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Kenneth Kreuzer, PhD, is Emeritus Professor of Biochemistry at Duke University. Ken grew up in Western New York, received his Bachelor of Science degree in Biology from MIT (1974) and his PhD in Genetics from the University of Chicago (1978). His graduate research provided some of the earliest evidence that the antibacterial quinolones act by poisoning the enzyme DNA gyrase, and his postdoctoral research at the University of California, San Francisco, identified replication origins of bacteriophage T4. As an independent investigator for three decades at Duke University, Kreuzer and his lab made contributions concerning cytotoxic mechanisms of topoisomerase inhibitors, the role of R-loops in DNA replication, connections between homologous recombination and DNA replication, and mechanisms of double-strand break repair. This research was supported by multiple grants from the NIH and other sources and resulted in over 100 publications. Most of these papers were co-authored by students and postdocs in his lab, who all went on to varied and successful careers of their own.

Ken is a Fellow of the American Academy of Microbiology and of the American Association for the Advancement of Science, and served as Interim Chair of the Duke Biochemistry Department (2007–2010). He has taken a special interest in mentoring and teaching throughout his academic career. He served as Director of the Duke University Summer Research Opportunities Program (1996–2003), the Duke Cell and Molecular Biology Graduate Program (2001–2006), the Duke Post-baccalaureate Research Education Program (PREP; 2003–2008), and as Co-Director of the Duke BioCoRE Program (Initiative to Maximize Student Development; 2013–2015). In honor of his graduate mentoring and diversity efforts, Ken has received the Samuel DuBois Cook Community Betterment Award, the Faculty Award for Graduate Teaching in the Duke Basic Biomedical Sciences, and the Duke University President’s Diversity Award. Since retiring from running an active lab in 2015, Ken and his wife Bev live in the mountains of Southwest Virginia with their dogs and ponies. In addition to writing this book, he has been enjoying woodworking, outdoor activities (golfing, hiking and kayaking), and spending quality time with friends in a beautiful rural setting.

Replicating And Repairing The Genome: From Basic Mechanisms To Modern Genetic Technologies

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