Читать книгу Complementary and Alternative Medicine (CAM) Supplement Use in People with Diabetes: A Clinician's Guide - Laura Shane-McWhorter - Страница 46

No adverse effects have been reported with aloe gel. One study evaluated renal and hepatic function, and there were no adverse effects.¹¹⁰ Aloe did not cause blood glucose to be excessively lowered when combined with the sulfonylurea glibenclamide (glyburide).¹¹⁰ Nevertheless, caution should be exercised by patients combining aloe with secretagogues. An unusual adverse effect was reported in a case of an individual taking aloe who experienced excessive intraoperative blood loss during surgery where sevoflurane was used. This may be due to the fact that both sevoflurane and aloe inhibit thromboxane A2, which may decrease platelet aggregation and prolong bleeding time.¹¹¹ There is also concern that inadvertent inclusion of aloe juice would produce a laxative effect and result in fluid or electrolyte disturbances.