Читать книгу Canine and Feline Epilepsy - Luisa De Risio - Страница 115

With urinary excreted toxins, diuresis and/or modification of the urine pH can enhance toxin excretion (O’Brien, 1998). Urine acidification can be achieved by administering ammonium chloride, 100 mg/kg PO for dogs and 20 mg/ kg PO for cats. Ammonium chloride should not be used in acidotic animals and overuse may result in ammonia toxicosis. Urine alkalinization can be achieved by administering sodium bicarbonate at 0.5 to 2 mEq/kg IV every 4 h. Possible adverse effects of systemic pH modulation need to be considered. The acid-base status of the animal must be monitored.