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Treatment is symptomatic and supportive, including dermal decontamination by bathing with a mild hand-dishwashing detergent and water (in case of dermal exposure to spot-on preparations), methocarbamol (Table 4.1), AEMs (see Table 4.1 and Chapters 12 and 24), fluid therapy and oxygenation (if necessary). Activated charcoal (Table 4.1) can be used in case of oral exposure. The use of intravenous lipid emulsion (Table 4.1) as adjunctive treatment to reduce tissue concentrations of permethrin has produced encouraging results in cats with permethrin toxicosis (Haworth and Smart, 2012; Kuo and Odunayo 2013).

Paresthesia to spot-on preparations may be treated by rubbing vitamin E, corn or olive oil on the application area (Wismer and Means, 2012).