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Presynaptic terminal bursting

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The amount of transmitter released is related to depolarization of presynaptic terminals. Changes in axon terminal excitability will have effects on synaptic excitation (Engelborghs et al., 2000). Abnormal bursts of action potentials occur in the axonal arborizations of thalamocortical relay cells during epileptogenesis. Since one thalamocortical relay cell ends on a large number of cortical neurons, synchronization can occur, which might play an important role in interictal–ictal transition (Engelborghs et al., 1998a).

Canine and Feline Epilepsy

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