Читать книгу Algorithms in Bioinformatics - Paul A. Gagniuc - Страница 57

The data mentioned above were determined by DNA sequencing approaches made so far. DNA sequencing is an ongoing process for several decades and the species chosen for sequencing are usually either of economic or research importance (or even of historical significance). There are many species that have not yet been sequenced, either due to their minor importance to humans or due to large genomes that cannot be easily managed. Usually, the size of the genetic material can be estimated by methods other than sequencing. One of these methods is flow cytometry, which estimates the weight of the genetic material [176]. This weight, expressed in picograms (pg), can then be converted to base pairs. One picogram is equal to 978 megabase pairs (1 pg = 978 Mbp) [177]. For instance, Paris japonica (flower) shows a genome weight of 152.23 pg, which suggests a genome size of 148 880 Mbp (152.23 pg × 978 Mbp = 149 Gbp) [178].