Читать книгу Handbook of Diabetes - Rudy Bilous - Страница 36

 Type 1 diabetes is one of a number of autoimmune endocrine diseases with a genetic and familial basis, although the majority of cases occur sporadically.

 Incidence rates vary from <5 to >60 per 100,000, generally being highest in northern latitudes.

 These rates are increasing more rapidly than can be explained by genetic factors alone.

 The autoimmune and genetic processes underpinning the disease are being unravelled.

 Environmental factors such as viruses and diet are responsible for some of the increase.

 Preventative trials have been disappointing but more targeted approaches are ongoing.