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Environmental and maternal factors

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Although genetic factors are undoubtedly important, the rapidly increasing incidence rates for type 1 diabetes at a younger age strongly suggest that external or environmental factors are playing a part. Much of the evidence that links environmental factors with the aetiology of type 1 diabetes is circumstantial and associative, based upon epidemiology and animal research. The factors most often implicated are viruses, and diet and toxins, but a number of other influences, such as early feeding with cow’s milk have been investigated (Table 6.3). These associations remain unexplained but may add support to the hygiene and accelerator hypotheses (see below).

Handbook of Diabetes

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