Читать книгу Handbook of Diabetes - Rudy Bilous - Страница 40

 Addison’s disease

 Graves’ disease

 Hypothyroidism

 Hypogonadism

 Pernicious anaemia

 Vitiligo

 Autoimmune polyglandular syndromes, types 1 and 2

 Coeliac disease

The mechanisms leading to autoimmunity have not been elucidated, and are almost certainly multiple with different factors operating in different individuals. What is clear is that exposure to environmental factors impacts upon genetically susceptible individuals to trigger an inflammatory response that ultimately leads to β cell loss and symptomatic diabetes.