Читать книгу Principles of Virology, Volume 2 - Jane Flint, S. Jane Flint - Страница 104

Researchers have found that Zika virus genetic material can be identified in tears of infected mice. This finding perhaps explains why some Zika-infected patients develop uveitis, a serious eye disease that can lead to permanent blindness, as well as less serious eye disorders such as retinal damage or optic nerve inflammation. Moreover, detection of viral nucleic acid in tears suggests that the eye might be a reservoir for Zika, and thus a portal for virus shedding. Of note, this has yet to be confirmed in humans, and presence of genetic material does not indicate that infectious virus is present. Nevertheless, the identification of a new potential “way out” for viruses indicates that viruses may be able cross numerous host barriers to access tear ducts, and may pose challenges for commonplace procedures such as corneal transplants. Adenoviruses can also be found in tears of individuals suffering from “pink eye,” the common name given for adenoviral conjunctivitis.

Figure 2.22 Mat herpes. An example of a herpesvirus infection on the arms of a young wrestler, called herpes gladiatorum. It should probably be called “herpes not-glad-at-allum.” Reprinted from Morse D, Vangipuram R, Tyring SK. 2019. Eur J Intern Med 60:e1e2, with permission.