Читать книгу Autologous Blood Concentrates - Arun K Garg - Страница 19
Ongoing Controversies
ОглавлениеSince the mid-1990s, clinicians have used an assortment of PRP preparations in several different therapies, ranging from oral and maxillofacial surgery and implantology to orthopedic surgery, burn treatment and the treatment of other wounds difficult to heal, soft tissue cosmetic surgery, soft tissue disease and injuries, and tissue engineering. Invariably, the literature that documents these therapies calls not only for high-level studies to better measure the efficacy of the variety of PRP therapies but also for standardizing the preparation and application of platelet-derived products.1–4
Any discussion of PRP application must be preceded by a review of platelet sequestration principles. Only then can a discussion of progress toward consensus on PRP protocols take place. Such an approach reveals that the clinical preparation and application of PRP across medical disciplines is a dynamic, evolving process, and that we disrupt this dynamism at our medical/scientific peril. Too-hasty attempts to reach consensus could inhibit researchers’ efforts to discover the full potential of PRP and other biologic therapies.