Читать книгу Autologous Blood Concentrates - Arun K Garg - Страница 6

In the nearly 25 years since Bob Marx and I developed the original formula for PRP, I have followed its gradual evolution from controversial idea to vital wound healing agent with keen interest—not unlike an anxious parent. In 2005, our co-authored book—Dental and Craniofacial Applications of PRP (Quintessence)—introduced the concept of platelet-rich plasma (PRP) to the world and provided scientific and clinical proof of its efficacy. Together, we spent the next decade training other clinicians on the proper use of PRP.

Everything changed in 2010, when it became public knowledge that PRP was the secret to Tiger Woods’s speedy recovery from a torn ACL. Commercial interests quickly co-opted the conversation, drowning out the voices of those who, like Marx and me, did not want to see this low-cost biotechnology exploited by profit-hungry manufacturers of centrifuge devices. There was also an enormous amount of misinformation being promulgated by certain medical/dental experts who recognized the enormous therapeutic potential of autologous growth factors and seized the opportunity to establish a name for themselves in the scientific community. The medical literature became saturated with articles introducing new terminology to describe slightly modified growth factor compositions, often without much (if any) additional clinical benefit. The result was an alarming lack of standardization in protocols, a nomenclature best described as an alphabet soup of acronyms, and an overwhelming sense of confusion among clinicians. In 2015, when I published the first edition of this book, my primary motivation was to “set the record straight.”

So the first edition of this book was my effort to refocus the conversation about platelet-derived therapies in order to make PRP accessible again to the practicing clinician. In titling the book, I made the major concession of using a generic term—autologous blood concentrates—as a way to signal my desire to focus on the science and not the politics. I wanted the book to reach clinicians regardless of which machine or nomenclature they were most familiar with.

In the world of regenerative biotechnology, 6 years is a very long time, and much has happened since the first edition of this book was published. This new second edition has been thoroughly revised, updated, and expanded to reflect current understanding, applications, and protocols of PRP for clinicians who have been using or wish to start using PRP in their practice. The centerpiece of this edition is a completely new chapter that details the step-by-step formulas and processes for preparing eight configurations of PRP and the specific indications for using each one. How and when to apply the various configurations in clinical dentistry—for soft tissue preservation, hard tissue preservation and regeneration, and facial rejuvenation procedures—is the subject of subsequent chapters. Because the use of PRP requires the clinician or an assistant to perform a venipuncture, the final chapter is a comprehensive guide to the principles and practice of phlebotomy.

I continue to engage in clinical PRP research, both in my private practices and through my charitable foundation, and will remain a passionate advocate for its use for the benefit of patients everywhere.