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Reticular Formation

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The RF has no single overriding function – and no single condition becomes apparent when it is damaged. It is a control centre, a polysynaptic network within the thalamus, hypothalamus, brainstem and cord involved in:

 Respiratory and cardiovascular control

 Sleep, wakefulness, arousal and mood

 Pattern generation – reflex activities, for example chewing, swallowing, conjugate gaze

 Micturition, bowel and sexual function

 Sensory modulation (see Gate control below, and Chapter 23)

 Autonomic and reflex activity (Chapter 24).

Essential anatomy and neurotransmitters: Figure 2.11 The raphe nuclei (pronounced ‘raffay’ = a seam in Greek) are the major source of serotoninergic neurones in the neuraxis.

Neurology

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