Читать книгу Neurology - Charles H. Clarke - Страница 50
Nucleus Accumbens, Septal Region and Basal Forebrain
ОглавлениеStimulation of areas of the ventral striatum (nucleus accumbens, ventral olfactory tubercle, ventral caudate and putamen) can lead to a sense of well‐being akin to a shot of heroin, attributed to excessive dopamine release.
Stimulation of the septal region in man produces pleasurable sexual sensations and/or orgasm. In animals, destructive lesions cause extreme anger – known as septal rage.
The basal forebrain lies between the olfactory tracts and the amygdala. The magnocellular basal nucleus of Meynert and its cholinergic neurones extend throughout the cortex. These magnocellular basal nuclei, septal nuclei and neurones, and an area known as the diagonal band of Broca are also called basal forebrain nuclei. These nuclei exert tonic cholinergic activity within the cortex, and thus maintain wakefulness.