Читать книгу Dental Neuroimaging - Chia-shu Lin - Страница 48

Just like prosthodontic treatment, the success of orthodontic treatment is associated with patients' adaptation to the oral appliance. Again, the neuroimaging findings revealed that the use of the oral appliance is associated with an extended area of brain activation, not just confined to the somatosensory cortex (Horinuki et al. 2015; Ozdiler et al. 2019) (Table 1.3). In rats, experimental tooth movement was associated with changes in brain activity of the secondary somatosensory cortex and the insula (Horinuki et al. 2015). Critically, the animal model revealed that during tooth movement, brain activity change was also associated with inflammation, as identified by the expression of the inflammatory factors and macrophage infiltration in the periodontal tissue (Horinuki et al. 2015). The findings have demonstrated the strength of combined neuroimaging and histological approaches, which help elucidate changes in clinical symptoms and signs related to dental treatment.