Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 300
Allograft or Autograft
ОглавлениеWhen using stem cells to treat tissue injury another important aspect to consider is whether to use tissue from the patient’s own body or from a donor. Cell differentiation potential is slower as age advances and this leads to weakening of tissues, which is one of the main reasons why older patients are at higher risk of tendon, ligament, or cartilage injury. Using stem cells from such patients will not bring about the desired repair to tissue. However, the use of stem cells from donors would mean that there is a risk of transferring genetic diseases that may exist in the donor. When stem cells from mice that were prone to osteoporosis were transferred to mice not prone to osteoporosis, the recipient mice developed the condition, indicating that stem cells can transfer genetic diseases. The use of stem cells in the treatment of cartilage, tendon, or ligament injuries is very important, not only among humans but also among animals that suffer tissue injury.