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Administration of plasma
ОглавлениеFrozen plasma should be thawed at 30–37°C, in a water bath prior to administration to avoid precipitation of proteins which can occur when thawed at a higher temperature, (e.g. in a microwave).
Plasma transfusions should be administered using a blood administration set with a filter to reduce the number of clots transfused. Blood clots travel through the systemic circulation and lead potentially to cardiac side effects or pulmonary artery obstruction resulting in fatal incidents.
The plasma transfusion should be started at a rate of 0.3–0.5 mL/kg/ for the first 10–20 minutes. During this time the horse should be continuously monitored for signs of adverse reactions and a brief physical examination should be performed every 5 minutes. Parameters that should be monitored and should not increase during that time include heart rate, respiratory rate and temperature. The occurrence of respiratory distress, cardiac arrhythmias, urticaria, muscle tremors, salivation and coughing should also be monitored. If no reaction occurs, the plasma can be administered faster.