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Differential Diagnosis

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The differential diagnosis of lichen planus includes other disorders that may show intraepithelial lymphocytic infiltration, such as drug injury, reflux, infections, Crohn’s disease and lymphocytic esophagitis. Clinical correlation is necessary, with particular attention to other mucocutaneous findings, medication or IBD history, location of injury, and response to therapy.

Differentiating bullous diseases from sloughing esophagitis requires clinical and/or IF correlation.

Gastrointestinal Pathology

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