Читать книгу Gastrointestinal Pathology - Группа авторов - Страница 102

Esophageal lichen planus has a tendency to cause persistent dysphagia and stricture formation. Systemic treatment is usually required to prevent stricturing disease. Injection of corticosteroids and a response to oral fluticasone have been reported. Squamous cell dysplasia and carcinoma can develop and long‐term follow‐up is advised.

Mucosal pemphigus vulgaris may remain localized to the mucous membranes or progress to skin involvement. Corticosteroids and immunosuppressive agents are considered first‐line treatments.

In epidermolysis bullosa, stricturing disease is common and treatment is symptomatic. Although these patients are at increased risk of skin cancer, esophageal carcinoma is rarely reported.

Scleroderma‐associated chronic GERD can lead to Barrett's esophagus with an increased risk of esophageal adenocarcinoma.