Читать книгу Gastrointestinal Pathology - Группа авторов - Страница 96

The squamous epithelial cytologic atypia may mimic carcinoma, which can be of particular concern for recurrent or persistent tumor in patients being treated for primary esophageal carcinomas, as radiation changes and neoplasia can coexist. Review of the prior tumor histology, if available, and assessment for evidence of invasion can be helpful.

The nuclear changes may also resemble viral infection, particularly Herpes simplex, which can be excluded by appropriate immunohistochemical stains for HSV.