Читать книгу Gastrointestinal Pathology - Группа авторов - Страница 87

Graft versus host disease (GVHD) is an important complication of allogeneic stem cell transplantation, leading to considerable morbidity and mortality. Gastrointestinal tract involvement is frequent, and endoscopy with biopsy plays a central role in the diagnosis and management of patients with suspected GVHD. Although the pathologic features of GVHD are well described in glandular mucosa, they are less so for the esophagus. Manifestations of esophageal injury may occur in the acute or chronic phases of GVHD. Diagnosis requires correlation of the clinical and pathologic features.