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Clinical and Endoscopic Characteristics

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About 75% of patients present with esophageal symptoms, most commonly dysphagia or odynophagia, which may raise the suspicion of eosinophilic esophagitis. Similarly, the endoscopic impression may suggest eosinophilic esophagitis, with the presence of rings, furrows, plaques, and strictures.

Table 2.6 Conditions associated with esophageal lymphocytosis (lymphocytic esophagitis).

GERD
Medications
Infection
Motility disorders
Immune‐mediated disorders (e.g. CVID)
Lichen planus/lichenoid esophagitis
Crohn's disease (pediatric)
Celiac disease (pediatric)

Figure 2.14 Characteristic histology of lymphocytic esophagitis.

Gastrointestinal Pathology

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